Osimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer
Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer
First author: Solange Peters
Brigatinib versus Crizotinib in ALK-Positive Non–Small-Cell Lung Cancer
First author: D.R. Camidge
AURA3
OSIM vs peme+plt
L2
Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
First-Line Lorlatinib or Crizotinib in Advanced ALK-Positive Lung Cancer
First author: Alice T. Shaw
CheckMate 017
NIVO vs doce
L2
Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer
First author: Julie Brahmer
CheckMate 026
NIVO vs PCT
L1
First-Line Nivolumab in Stage IV or Recurrent Non–Small-Cell Lung Cancer
First author: D.P. Carbone
CheckMate 057
NIVO vs doce
L2
Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer
First author: H. Borghaei
CheckMate 227
NIVO+IPIL vs chemo
L1
Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden
First author: M.D. Hellmann
Treatment Outcomes and Safety of Mobocertinib in Platinum-Pretreated Patients With EGFR Exon 20 Insertion–PositiveMetastatic NSCLC
First author: Caicun Zhou
FLAURA
OSIM vs erlo or gefi
L1
Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC
First author: S.S. Ramalingam
IMpower110
ATEZ vs chemo
L1
Atezolizumab for First-Line Treatment of PD-L1–Selected Patients with NSCLC
First author: Roy S. Herbst
IMpower150
ATEZ+BEVA+chemo (ABCP) vs BEVA+chemo (BCP)
L1
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
First author: M.A. Socinski
KEYNOTE-024
PEMB vs PCT
L1
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
First author: Martin Reck
KEYNOTE-189
PEMB+peme/pct vs PLB+peme/pct
L1
Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer
KEYNOTE-407
PEMB+carb/pacl vs PLB+carb/pacl
L1
Pembrolizumab plus Chemotherapy for Squamous Non–Small-Cell Lung Cancer
First author: L. Paz‑Ares
LIBRETTO-001
SELP vs NA
L3
Efficacy of Selpercatinib in RET Fusion–Positive Non–Small-Cell Lung Cancer
Crizotinib versus Chemotherapy in Advanced ALK-Positive Lung Cancer
First author: Alice T. Shaw
PROFILE 1014
CRIZ vs chemo
L1
First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer
First author: Benjamin J. Solomon