AVOREN
BEVA+INF vs PLB+INF
L1
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma
First author: Bernard Escudier
CLEAR
LENV+PEMB vs suni
L1
Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma
CheckMate 025
NIVO vs ever
L2
Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma
First author: R.J. Motzer
CheckMate 214
NIVO+IPIL vs suni
L1
Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma
First author: R.J. Motzer
CheckMate 9ER
NIVO+CABO vs suni
L1
Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma
First author: T.K. Choueiri
JAVELIN Renal 101
AVEL+AXIT vs SUNI
L1
Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma
First author: Robert J. Motzer
KEYNOTE-426
PEMB+AXIT vs sunit
L1
Pembrolizumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma
Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma
First author: T.K. Choueiri